First trimester · weeks 1–13 guide

First trimester

Weeks 1 through 13

The first trimester spans weeks 1–13 — conception, implantation, and the formation of all major organ systems. Nausea and deep fatigue are common; folic acid and the first-trimester screen are the key milestones.

Months in this trimester

Key milestones

  • Conception around week 3; implantation in week 4 — hCG begins to rise.
  • Neural tube forms in weeks 5–6 — folic acid matters most here.
  • Fetal heartbeat visible on ultrasound at week 6 (100–160 bpm).
  • Nuchal translucency (NT) screening at weeks 11–13+6.
  • By the end of week 13: ~7.4 cm, ~23 g. All major organ systems are in place.

Recommended prenatal care

  • First prenatal visit at 6–8 weeks — confirm gestational sac and heartbeat.
  • Initial blood panel — rubella, hepatitis B, HIV, blood type, CBC.
  • NT ultrasound at 11–13+6 weeks.
  • First-trimester combined screen (blood markers + NT).
  • NIPT (cell-free DNA) is generally available from week 10.

Jump to trimester

Textbook averages. Individual variation is wide and this is not medical advice — confirm with your OB.